The Spike: An Epic Journey Through the Brain in 2.1 Seconds

The Spike: An Epic Journey Through the Brain in 2.1 Seconds

by Mark Humphries
The Spike: An Epic Journey Through the Brain in 2.1 Seconds

The Spike: An Epic Journey Through the Brain in 2.1 Seconds

by Mark Humphries

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Overview

The story of a neural impulse and what it reveals about how our brains work

We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them.

Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival.

Traversing neuroscience’s expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.


Product Details

ISBN-13: 9780691241487
Publisher: Princeton University Press
Publication date: 01/24/2023
Pages: 232
Sales rank: 1,042,964
Product dimensions: 5.20(w) x 7.90(h) x 0.80(d)

About the Author

Mark Humphries is Chair in Computational Neuroscience at the University of Nottingham. He is the founding editor of The Spike, a Medium online publication. He lives in Sheffield, England. Twitter @markdhumphries

Table of Contents

Chapter 1 Introduction 1

Chapter 2 All or Nothing 11

Chapter 3 Legion 28

Chapter 4 Split Personality 45

Chapter 5 Failure 67

Chapter 6 The Dark Neuron Problem 82

Chapter 7 The Meaning of Spike 97

Chapter 8 A Moving Experience 121

Chapter 9 Spontaneity 134

Chapter 10 But a Moment in Time 144

Coda. The Future of Spikes 164

Acknowledgments 175

Notes 177

Index 213

What People are Saying About This

From the Publisher

"In this fascinating, roller-coaster ride through the most fundamental component of our nervous systems, Mark Humphries takes us to the frontiers of neuroscience. A brilliant achievement."—Matthew Cobb, author of The Idea of the Brain: The Past and Future of Neuroscience

"This book is truly wonderful. Mark Humphries takes us on a magical, demystifying tour of the brain, letting us tag along on a neural signal’s journey from eyeball to hand—as when you see a mosquito and swat it. Rollicking but deftly organized, The Spike is cast in everyday, easygoing language yet backed by tight science and state-of-the-art insights. This book's fresh approach will charm novices as well as old neurobiological hands."—Patricia S. Churchland, author of Conscience: The Origins of Moral Intuition

"The Spike is a fun yet deeply informative account of the electrical journey that information takes as it passes into our eyes and through our mind, and ultimately leads us to act. Drawing on the latest neuroscientific discoveries and theories, Humphries tells a compelling story of how minute changes in electrical signals in the brain give rise to our thoughts and actions."—Russell A. Poldrack, author of Hard to Break: Why Our Brains Make Habits Stick

"The Spike gives a brilliant overview of our current understanding of brain function, from perception to action, based on our knowledge of systems neuroscience. Conveying ideas and concepts with impressive clarity, Humphries covers an astonishing amount of scientific literature. A joy to read."—Matthias Hennig, University of Edinburgh

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